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帕金森病流行现状

Epidemiology of Parkinson’s disease

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【作者】 刘疏影陈彪

【Author】 LIU Shu-ying;CHAN Piu;Department of Neurology,Xuanwu Hospital,Capital Medical University;

【机构】 首都医科大学宣武医院神经内科

【摘要】 帕金森病是一种老年人群常见的中枢神经系统变性病,主要引起静止性震颤、肌强直、运动迟缓和姿势步态异常等运动障碍,同时伴有大量非运动症状。帕金森病患病率、发病率随年龄的增长而成倍升高,随着老龄化社会的到来,老龄人口的增加导致全球(特别是中国)帕金森病患病率呈明显上升态势,正确认识帕金森病流行病学特征有助于积极应对这一挑战。本文对全球帕金森病患病率、发病率、病死率等流行病学现状和各地区间的差异进行概述,并重点介绍我国帕金森病流行现状、未来趋势和经济负担。

【Abstract】 Parkinson’s disease(PD) is a common neurodegenerative disease in the agedpopulations, which is characterized by resting tremor, rigidity, bradykinesia and abnormal gait, accompaniedby a variety of non- motor symptoms(NMS). The prevalence and incidence of PD rise sharply with theincrease of age. In the advent of global aging, the rapid growing of elderly populations results in a risingnumber of PD patients, especially in China. A correct understanding of the epidemiology of PD helps torespond to this challenge actively. This article aims to provide an overview of the prevalence, incidenceand mortality of PD and their differences among regions. Special efforts are made to illustrate the currentstatus and future trends of the epidemiology and economic burden of PD in China.

【关键词】 帕金森病; 流行病学; 综述;

【Key words】 Parkinson disease; Epidemiology; Review;

【分类号】R742.5;R181.2;R195.4;

【基金】 国家高技术研究发展计划(863计划)项目(项目编号:2012AA02A514);国家重点基础研究发展计划(973计划)项目(项目编号:2011CB504100)~~

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