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多索茶碱与氨茶碱治疗支气管哮喘临床疗效的对比观察

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【作者】 谭磊

【机构】 广东省中山大学附属博济医院增城市人民医院

【摘要】 目的比较多索茶碱与氨茶碱治疗支气管哮喘的临床疗效。方法 112例支气管哮喘急性发作轻中度患者随机分为多索茶碱组和氨茶碱组各56例,两组在常规治疗的基础上分别给予多索茶碱和氨茶碱静滴,7d后比较两组的肺功能指标及临床疗效。结果多索茶碱和氨茶碱组的有效率分别为89.3%和73.2%,两组比较有统计学差异(P<0.05);治疗后两组患者的肺功能均有不同程度的改善,多索茶碱改善效果更好;治疗过程中多索茶碱组的不良反应发生率为7.1%,显著低于氨茶碱组(P<0.05)。结论多索茶碱用于治疗支气管哮喘轻中度急性发作疗效显著,起效快且不良反应少,值得在临床推广。

【Abstract】 Objective To compare the clinical effect of doxofylline and aminophylline in bronchial asthma.Methods 112 cases of bronchial asthma were randomly divided into doxofylline group and aminophylline group,56 cases in each group.Two groups were given doxofylline and aminophylline at the base of conventional treatment,the efficacy were compared after 7 days.Results The clinical cure rate of doxofylline group was 89.3%,significantly higher than aminophylline group(P<0.05).Two groups’ pulmonary function were improved after treatment,and doxofylline group was more better.The incidence rate of adverse reaction of doxofylline group was 7.1%,significantly lower than aminophylline group(P<0.05).Conclusion The clinical effect of doxofylline in bronchial asthma is satisfactory,recovery faster and less adverse reactions,is worthy of clinical use.

【关键词】 多索茶碱; 氨茶碱; 支气管哮喘; 肺功能;

【Key words】 Doxofylline; Aminophylline; Bronchial asthma; Pulmonary function;

【分类号】R974.3;R562.25;R452;

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